FDA Determines Codeine, Tramadol Unsafe For Children
Apr 22, 2017, 01:42
The Food and Drug Administration on Thursday sharply ratcheted up its warnings about giving children prescription medicines with codeine and tramadol, saying the drugs could cause severe breathing problems and death.
Douglas Throckmorton, MD, deputy center director for regulatory programs, Center for Drug Evaluation and Research said in a statement that they have discovered that some children who take medicine containing codeine or tramadol have experience life-threatening respiratory depression and even death. The new warning further limits the agency's previous restriction of codeine use in children younger than age 18.
FDA announced Thursday that it is restricting the use of codeine and tramadol medicines in children.
Codeine is a narcotic painkiller and cough suppressant with similar effects to morphine and hydrocodone, which are strong opioid medication. Single-ingredient codeine and all tramadol-containing products are FDA-approved only for use in adults. There are serious risks associated with the drugs, including slowed or hard breathing and death, which appear to be a greater risk in children younger than aged 12 years.
In a related safety memo, the FDA explained that all manufacturers of codeine and tramadol would be required to add several new warnings to their labels. Codeine labeling already warns against post-surgical use for kids. For children ages 12-18, and for breastfeeding mothers, the FDA said, the use of these medications should be limited. Besides a change saying that the drugs shouldn't be used in children under 12, the mandated changes include a new warning for tramadol saying it shouldn't be used in children younger than 18 for post-surgical pain after the removal of tonsils and adenoids.
"Today's actions build on a better understanding of this very serious safety issue, based on the latest evidence", Throckmorton said. It also identified three deaths and six other cases of serious breathing problems reported between January 1969 and March 2016 in children taking tramadol.
At the time, pharmacist Maria Pruchnicki, an associate professor at the Ohio State University College of Pharmacy, told NPR's Rob Stein, "My concern, were I to be prescribing codeine in children, would be that I would, frankly, kill them".
The Hooker Chamber of Commerce will be hosting an Easter Egg Hunt April 15 from 1 p.m.to 2 p.m.at the chamber building at 102 E. The kids can redeem the eggs at the matching store to receive prizes such as money, candy and small gifts.
There are no plans for either parent to move and they have no desire to uproot their 10-year-old son from his life in NY . La La and Carmelo Anthony have reportedly made a decision to separate after seven years of marriage.
While no current dealers will lose their license, new licenses wouldn't be issued until the total decreases below the cap. The proposal also advocates the creation of a retail license for e-cigarettes, as well as limiting the number of sellers.
That app, officially known as Microsoft To-Do (codenamed "Project Cheshire") has been in private testing for close to a year. Only after things get settled with Microsoft To-Do, and the company gets confident over the new product, they will let fall.
However, it's now only available in California where the foundations of a hydrogen refilling infrastructure are slowly being laid. Honda has set a target of selling 75,000 Clarity cars - fuel cell, hybrid, or all-electric - annually, starting next year.
Nene also had another strong game , as he made all three of shots for seven points to go along with five rebounds. Atlanta's backcourt is simply too inexperienced to compete with a pair of All-Stars at the peak of their careers.
Lex Kerssemakers, CEO of Volvo Car USA, said in March that he was pushing for its first electric car to fall in the $40,000 range. Volvo's first electric auto will have a 100 kWh battery and be manufactured at its factory in Luqiao, China.
The order specifically asks the secretary to review waivers of these rules that exist in free-trade agreements. As per several USA reports, a majority of the H-1B visas every year is grabbed by Indian IT professionals.
On Tuesday analysts at HSBC reiterated Barclays PLC's (LON:BARC) shares as "Buy" in a research note issued to investors. The stock of Ithaca Energy Inc (LON:IAE) has "Outperform" rating given on Wednesday, January 20 by RBC Capital Markets.
The truth is out there: 'The X-Files is coming back
The new installment will consist of 10 episodes, giving writers more leeway in telling the story of Fox Mulder and Dana Scully. It seems the fans agree, as the previous season grabbed tons of viewers, which trumps critical opinion any day of the week.
French candidates boost security ahead of tense vote
The nightmare scenario for global financial markets is a second-round duel between the equally sharp-tongued Le Pen and Melenchon. The race for the presidency features Francois Fillon , Emmanuel Macron, Benoit Hamon, Jean-Luc Melenchon, and Marine Le Pen.
Georgia special election goes to runoff
He will face Republican challenger Karen Handel , a former Georgia secretary of state who attracted 19.8 percent of the vote. She added that when it comes to balancing the budget and repealing Obamacare, both Handel and Trump are for the people.
Prince Harry spotted visiting Meghan Markle in Toronto
That move could be another sign that she is trying to get her affairs in order before a potential move to London, Duboff said . Princess Kate gave up her job as an accessories buyer before she became engaged in 2010 to Prince William .
Google Earth gets revival with tools for exploration
Instead of the typical flat satellite imagery, you get handsome shots that make Google Earth feel more immersive than ever before. You might find yourself in Valencia, Spain and stumble on the attractive Ciudad de las Artes y Las Ciencias.
Arkansas AG working to overturn decisions halting executions
Bruce Earl Ward and Don William Davis Jr. were scheduled to die Monday night in the first two of eight executions over 11 days. Nine death row prisoners brought the case to the state, arguing that midazolam could expose them to "severe pain".
Shark kills 17-year-old surfer in southern Australia
It was reported that she lost a leg, was treated by paramedics on the beach at Bandy Creek and was then taken to the hospital. A beach on Western Australia's south coast, near Esperance , will remain closed today after a fatal shark attack.
ProPublica, New York Daily News win Pulitzers
This undated photo shows one of the photos in the series that won the Pulitzer Prize for Feature Photography by E. Only the victor in the Public Service category of the Journalism competition is awarded a gold medal.